The V410L knockdown resistance mutation occurs in island and continental populations of Aedes aegypti in West and Central Africaby Ayres et al.
These results suggest that populations carrying the same kdr mutations may respond differently to the same insecticide, stressing the need for complementary studies when assessing the impact of kdr resistance mechanisms in the outcome of insecticide-based control strategies.
Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challengesby Dusfour et al.
Based on a plan developed for malaria vectors, here the authors propose some key activities to establish a global plan for insecticide resistance management in Aedes species.
Insecticide resistance is mediated by multiple mechanisms in recently introduced Aedes aegypti from Madeira Island (Portugal)by Seixas et al.
This study showed the up-regulation of several detoxification genes of multiple enzyme families associated with metabolic resistance, and the presence of the two kdr mutations, with the F1534C being fixed. Another suggested mechanism probably involved in the resistance phenotype is cuticle thickening, as several cuticle genes were found overexpressed. This study reinforces the importance of alternative control strategies to suppress Ae. aegypti population and thus reduce the likelihood of arbovirus transmission in the region.