Yellow fever virus re-emergence and spread in Southeast Brazil, 2016-2019
by Giovanetti et al.This study provides an understanding of how YFV initiates transmission in new Brazilian regions and illustrates that genomics in the field can augment traditional approaches to infectious disease surveillance and control.
Estimating the risk of arbovirus transmission in Southern Europe using vector competence data
by Mariconti et al.Based on vector competence data and vector distribution, the auhtors generate a prediction risk map for CHIKV stressing the fear of CHIKV and to a lesser extent, of other arboviruses for Europe, calling us for new public health strategies.
For this study researchers collected nasopharyngeal specimens from 282 children aged ≤5 years with acute respiratory tract infection (ARI) during 2005 to 2006 in one of the largest Brazilian slums.
Zika virus threshold determines transmission by European Aedes albopictus mosquitoes
by Vazeille et al.Results in this study stress the poor ability of Ae. albopictus to sustain a local transmission of ZIKV in Europe and provide a promising tool to evaluate the risk of ZIKV transmission in future outbreaks.
This study reveals distinctive functions of lipin1 and lipin2 in cells of hepatic origin, a context in which they are often considered functionally redundant.
Zika Virus Outbreak on Curaçao and Bonaire, a Report Based on Laboratory Diagnostics Data
by Lim et al.ZIKV cases confirmed by qRT-PCR indicate that the virus was circulating on Curaçao between at least December 2015 and March 2017, and on Bonaire between at least October 2016 and February 2017, with peak cases occurring in November 2016.
Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges
by Dusfour et al.Based on a plan developed for malaria vectors, here the authors propose some key activities to establish a global plan for insecticide resistance management in Aedes species.
REALM: An Altmetrics-based Framework to Map Science Impacts on Society. A Case Study on Zika Research
by Passos Maia et al.In this paper the authors describe an altmetrics-based framework which allows the identification of specialists and important research in specific research scenarios.
Yeast-produced subunit protein vaccine elicits broadly neutralizing antibodies that protect mice against Zika virus lethal infection
by Zhang et al.Yeast-derived EDIII is a safe and effective ZIKV vaccine candidate with desirable production traits.
A New High-Throughput Tool to Screen Mosquito-Borne Viruses in Zika Virus Endemic/Epidemic Areas
by Moutailler et al.The authors present and show a new tool that can detect endemic and epidemic viruses in different mosquito species in an epidemic context. This fast and low-cost method can be suggested as a novel epidemiological surveillance tool to identify circulating arboviruses.
High specificity and sensitivity of Zika EDIII-based ELISA diagnosis highlighted by a large human reference panel
by Denis et al.Researchers developed a ZEDIII-based ELISA that can discriminate between past or current DENV and ZIKV infections, allowing the detection of a serological scar from other flaviviruses. This could be used to confirm exposure of pregnant women or to follow the spread of an endemic disease.
This study provides a simple and cost‐effective approach to improve the specificity of resistance allele's detection in multi‐resistant populations while reducing false positives frequently arising when comparing populations showing divergent genetic backgrounds.
16th International Dengue Course organized by the Institute of Tropical Medicine "Pedro Kourí"
by ZIKAllianceComplex Scenario of Homotypic and Heterotypic Zika Virus Immune Enhancement
by Marques & DrexlerLetter to the Editor
Evolution and biological significance of flaviviral elements in the genome of the arboviral vector Aedes albopictus
by Houé et al.Results from this study show a complex association between NIRVS and DENV/CHIKV opening a new avenue for investigating the functional role of NIRVS as antiviral elements shaping vector competence of mosquitoes to arboviruses.
In this article, the authors applied their optimized viral metagenomics protocol (NetoVIR) to compare the virome of single and pooled Aedes aegypti and Culex quinquefasciatus mosquitoes collected from different locations in Guadeloupe, in 2016 and 2017.
ZIKV infection induces robust Th1-like Tfh cell and long-term protective antibody responses in immunocompetent mice
by Liang et al.This study suggests that specific modulation of the Th1-like Tfh cell response during infection or vaccination may augment the induction of antiviral antibody response to ZIKV and other viruses.
Sloths host Anhanga virus‐related phleboviruses across large distances in time and space
by de Oliveira Filho et al.In this study, researchers confirmed the association of Anhanga virus (ANHV)‐related viruses with both extant two‐toed sloth species in the Choloepus genus across 3,000 km distance and half a century between the both detections.
Impact of Zika Virus Emergence in French Guiana: A Large General Population Seroprevalence Survey
by Flamand et al.This study described a large-scale representative ZIKV seroprevalence study in South America from the recent 2015–2016 Zika epidemic. The findings reveal that the majority of the population remains susceptible to ZIKV, which could potentially allow future reintroductions of the virus.