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PARTNER N° |
4 |
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NAME OF INSTITUTION |
Erasmus Medical Center (EMC) |
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BRIEF DESCRIPTION OF THE TEAM |
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Erasmus MC is the largest university medical center in The Netherlands. It is the legal entity of the department of viroscience, headed by Marion Koopmans. The Department of Viroscience at Erasmus MC employs over the 100 people in the research unit, which runs a multidisciplinary research program on viral infections of humans and animals, with specific interests in viral zoonoses, pathogenesis and transmission as well as natural and vaccine‐induced immunity. The research teams consist of medical doctors, veterinarians, molecular biologists, epidemiologists, virologists, immunologists, pathologists, ecologists, and bio‐informaticians. The research unit focuses on two main pillars: 1) personalized health, covering the main viral diseases in high risk populations, and 2) one health, covering (emerging) arboviral and zoonotic diseases. The diagnostic unit of the department employs approx. 45 qualified personnel (4 consultant Medical microbiologists, 2 consultant Infectious disease specialists (MD), 3 Post‐docs, 25 technicians, 12 support staff) focussing on routine virus diagnostics, including development and implementation of new virus diagnostic assays. The department has two BSL3 laboratories, one animal BSL3 laboratories, multiple BSL2 laboratories (including animal BSL2 facilities).
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KEY CONTACT PERSON(S) |
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Key scientific contact person 1 (Team leader) |
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Name |
Prof. Dr. Marion Koopmans (female) |
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Photo |
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Position in the Institution |
Head of Department of Viroscience |
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Email address |
m.koopmans@erasmusmc.nl |
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Phone number |
+31 10 704 4066 |
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Mobile phone |
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Key scientific contact person 2 |
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Name |
Prof. Dr. Eric van Gorp |
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Photo |
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Position in the Institution |
Specialist in Internal Medicine and Infectious Diseases |
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Email address |
e.vangorp@erasmusmc.nl |
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Phone number |
+31 10 703 0310 |
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Mobile phone |
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Key scientific contact person 3 |
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Name |
Dr. Bart Haagmans |
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Photo |
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Position in the Institution |
Workgroup leader |
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Email address |
b.haagmans@erasmusmc.nl |
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Phone number |
+31 10 704 4004 |
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Mobile phone |
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Key scientific contact person 4 |
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Name |
Dr. Byron Martina |
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Photo |
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Position in the Institution |
Workgroup leader |
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Email address |
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Phone number |
+31 10 704 4279 |
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Mobile phone |
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Key scientific contact person 5 |
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Name |
Dr. Chantal Reusken |
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Photo |
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Position in the Institution |
Work group leader |
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Email address |
c.reusken@erasmusmc.nl |
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Phone number |
+31 10 704 4068 |
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Mobile phone |
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Key scientific contact person 6 |
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Name |
Dr. Matt Cotten |
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Photo |
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Position in the Institution |
Work group leader |
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Email address |
m.cotten@erasmusmc.nl |
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Phone number |
+31 10 704 4066 |
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Mobile phone |
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Key scientific contact person 7 |
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Name |
Dr. Barry Rockx |
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Photo |
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Position in the Institution |
Work group leader |
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Email address |
b.rockx@erasmusmc.nl |
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Phone number |
+31 10 704 4066 |
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Mobile phone |
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Address |
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Postal address |
‘s Gravendijkwal 230 3015 CE ROTTERDAM |
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Roles |
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Role in the Consortium |
WP1 - Clinical Sciences, Epidemiology & Modelling |
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Task 1.1: Pregnant women cohort |
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Sub-task: |
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Role: contributor Prof. Dr. Eric van Gorp |
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Task: 1.2 Cohort of children from pregnant women cohort |
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Sub-task: |
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Role: contributor Prof. Dr. Eric van Gorp |
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Task 1.3: Natural History Cohort |
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Sub-task: |
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Role: contributor Prof. Dr. Eric van Gorp |
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WP2 - Clinical biology & immunology |
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Role: WP-leader Prof. Dr. Marion Koopmans |
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Task 2.1: Establishment of laboratory support of cohort studies |
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Role: Task-leader Dr. Chantal Reusken |
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Sub-task 2.1.1: Definition and follow-up of procedures and diagnostic algorithms |
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Role: sub-task-leader Dr. Chantal Reusken |
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Sub-task 2.1.2: Preparation & coordination of the different laboratory sites |
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Role: sub-task-leader Dr. Byron Martina |
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Sub-task 2.1.3: Data sharing platform and governance |
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Role: sub-task-leader Dr. Matt Cotten |
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Task 2.2: Description of natural history of infection & impact of previous flaviviral exposure |
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Role: Task-leader Dr. Byron Martina |
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Sub-task 2.2.1: Determination of kinetics of viral shedding and antibody response |
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Role: Task-leader Dr. Chantal Reusken |
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Sub-task 2.2.2: Pre- and post-natal diagnosis of congenital ZIKV infection |
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Role: contributor Dr. Chantal Reusken |
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Sub-task 2.2.3: Virus analysis by whole genome amplicon based sequencing in different body fluids (viral load, kinetics, metagenomics and analysis of minor viral variants) |
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Role: contributor Dr. Matt Cotten |
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Sub-task 2.2.4: Metagenomic analysis of viromes of patients with ZIKV virus infection with and without complications |
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Role: contributor Dr. Matt Cotten |
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Sub-task 2.2.5: Identification of biomarkers associated with infection or with complications: impact of prior immunity |
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Role: sub-task-leader Dr. Barry Rockx |
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Sub-task 2.2.6: Identification of biomarkers associated with infection or with complications: potential autoimmune markers |
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Role: sub-task-leader Dr. Barry Rockx |
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