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PARTNER N° |
14 |
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NAME OF INSTITUTION |
CNRS |
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BRIEF DESCRIPTION OF THE TEAM |
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LECA is a joint CNRS/University of Grenoble-Alpes laboratory hosting more than 50 full-time staff. With a strong experience in ecology, evolutionary biology and adaptation, and extensive links with European research organizations. The mosquito group of LECA has been involved in several research programs for studying insecticide resistance in mosquitoes allowing the LECA to become a respected research institution in the field with collaboration links extending worldwide. Under the management of Dr JP David, the mosquito group acquired a solid experience in studying the adaptation of mosquitoes to insecticides,with major skills in eco-toxicology, transcriptomics, genomics, genetics and functional biology. This group has a high expertise in applying next generation technologies for studying insecticide resistance in mosquitoesas demonstrated by recent publications. The group published more than 45 publications related to mosquitoes and insecticides since 2005. The LECA hosts brand new insectaries (50 m2, P2+ security level) and an insecticide testing platform. LECA also hosts fully equipped biochemistry and molecular biology laboratories together with a computing platform dedicated to the analysis of next generation sequencing data.
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KEY CONTACT PERSON(S) |
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Key scientific contact person 1 (Team leader) |
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Name |
Jean-Philippe DAVID |
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Photo |
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Position in the Institution |
CNRS permanent researcher (CR1) |
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Email address |
Jean-philippe.david@univ-grenoble-alpes.fr |
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Phone number |
+33 (0)4 76 51 44 59 |
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Mobile phone number |
+33 (0)6 85 88 94 30 (only in case of emergency, private number) |
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Postal address |
Laboratoire d'Ecologie Alpine (LECA) UMR 5553 CNRS-Université Grenoble-Alpes, Domaine universitaire de Saint Martin d'Hères France
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Role in the Consortium |
WP: 6 |
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Task: 6.4.1 and 6.4.2.1 |
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Sub-task: |
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WP6 – Task 6.4.1. Resistance to insecticides: LECA will be in charge of combining different next generation sequencing approaches for identifying novel insecticide resistance markers in Zika vectors and develop DNA-based diagnostic tests to monitor their frequency in natural mosquito populations. WP6 – Task 6.4.2.1. Counteract the antioxidant defense: LECA will contribute to test compounds that can affect mosquito redox homeostasis on mosquito lines originating from various places in the world and carrying different resistance mechanisms.
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