Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals
by Lanko et al.This study demonstrates for the first time that motor neurons support ZIKV replication and these cells are as a consequence of ZIKV replication destroyed by the virus, and that human iPSC derived neuronal cells offer a physiologically relevant system to assess the potential antiviral effect of small molecule inhibitors of viral replication that are being developed to clear ZIKV infections in the nervous system.
1st September 2017 •
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